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Retinal Targets ALDH Positive Cancer Stem Cell and Alters the Phenotype of Highly Metastatic Osteosarcoma Cells

Aldehyde dehydrogenase (ALDH) is a cancer stem cell marker. Retinoic acid has antitumor properties, including the induction of apoptosis and inhibition of proliferation. Retinal, the precursor of retinoic acid, can be oxidized to retinoic acid by dehydrogenases, including ALDH. We hypothesized that...

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Detalles Bibliográficos
Autores principales:	Mu, Xiaodong, Patel, Stuti, Mektepbayeva, Damel, Mahjoub, Adel, Huard, Johnny, Weiss, Kurt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706975/ https://www.ncbi.nlm.nih.gov/pubmed/26819566 http://dx.doi.org/10.1155/2015/784954

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