SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation

SUMOylation is recently found to function as a targeting signal for the degradation of substrates through the ubiquitin-proteasome system. RNF4 is the most studied human SUMO-targeted ubiquitin E3 ligase. However, the relationship between SUMO proteases, SENPs, and RNF4 remains obscure. There are li...

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Detalles Bibliográficos
Autores principales: Wang, Ming, Sang, Jing, Ren, Yanhua, Liu, Kejia, Liu, Xinyi, Zhang, Jian, Wang, Haolu, Wang, Jian, Orian, Amir, Yang, Jie, Yi, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707158/
https://www.ncbi.nlm.nih.gov/pubmed/26511642
http://dx.doi.org/10.1007/s13238-015-0216-7

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