Cargando…

The PI3K/Akt Pathway in Tumors of Endocrine Tissues

The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is a key driver in carcinogenesis. Defects in this pathway in human cancer syndromes such as Cowden’s disease and Multiple Endocrine Neoplasia result in tumors of endocrine tissues, highlighting its importance in these cancer types. This review ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Robbins, Helen Louise, Hague, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707207/ https://www.ncbi.nlm.nih.gov/pubmed/26793165 http://dx.doi.org/10.3389/fendo.2015.00188

Ejemplares similares

Editorial: Cell Signaling in Tumors of Endocrine and Endocrine-Responsive Tissues
por: Perks, Claire, et al.
Publicado: (2019)

Antidiabetic Effect of Artemether in Db/Db Mice Involves Regulation of AMPK and PI3K/Akt Pathways
por: Bai, Xiaolin, et al.
Publicado: (2020)

Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues?
por: Barker, Rachel M., et al.
Publicado: (2020)

Neuroprotective Role of the PI3 Kinase/Akt Signaling Pathway in Zebrafish
por: Chen, Shuang, et al.
Publicado: (2017)

Aberrant PI3Kδ splice isoform as a potential biomarker and novel therapeutic target for endocrine cancers
por: Ha, Siyoung, et al.
Publicado: (2023)

Effect of Codonopsis Radix and Polygonati Rhizoma on the regulation of the IRS1/PI3K/AKT signaling pathway in type 2 diabetic mice
por: Mao, Yong-po, et al.
Publicado: (2022)

Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy
por: Lu, Rui, et al.
Publicado: (2022)

Role of PI3K/Akt/mTOR pathway in mediating endocrine resistance: concept to clinic
por: Skolariki, Aglaia, et al.
Publicado: (2022)

Neural Cell Adhesion Molecule Regulates Osteoblastic Differentiation Through Wnt/β-Catenin and PI3K-Akt Signaling Pathways in MC3T3-E1 Cells
por: Cheng, Bin-Feng, et al.
Publicado: (2021)

Cross-Dysregulation of O-GlcNAcylation and PI3K/AKT/mTOR Axis in Human Chronic Diseases
por: Very, Ninon, et al.
Publicado: (2018)

Hypoxia signaling pathway: A central mediator in endocrine tumors
por: Watts, Deepika, et al.
Publicado: (2023)

PI3K/AKT/mTOR pathway activation in primary and corresponding metastatic breast tumors after adjuvant endocrine therapy
por: Beelen, Karin, et al.
Publicado: (2014)

Fibroblast growth factor 21 is expressed and secreted from skeletal muscle following electrical stimulation via extracellular ATP activation of the PI3K/Akt/mTOR signaling pathway
por: Arias-Calderón, Manuel, et al.
Publicado: (2023)

PI3K/AKT/mTOR pathway in tumor progression of oligodendrogliomas
por: Lisi, Lucia
Publicado: (2020)

Dysregulation of PI3K/Akt/PTEN Pathway in Canine Mammary Tumor
por: Kim, Soo-Hyeon, et al.
Publicado: (2021)

PI3K/AKT Pathway and Brain Malformations
por: Rice, Gavin B., et al.
Publicado: (2015)

The PI3K/Akt Pathway in Meta-Inflammation
por: Acosta-Martinez, Maricedes, et al.
Publicado: (2022)

Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression
por: Polo, María Laura, et al.
Publicado: (2015)

Insulin resistance, autophagy and apoptosis in patients with polycystic ovary syndrome: Association with PI3K signaling pathway
por: Tong, Cheng, et al.
Publicado: (2022)

Editorial: Stem Cells in Endocrine Tumors
por: Di Franco, Simone, et al.
Publicado: (2021)

Pathways to Endocrine Therapy Resistance in Breast Cancer
por: Haque, Md. Moquitul, et al.
Publicado: (2019)

HijAkt: The PI3K/Akt Pathway in Virus Replication and Pathogenesis
por: Dunn, Ewan F., et al.
Publicado: (2012)

PI3K: An Attractive Candidate for the Central Integration of Metabolism and Reproduction
por: Acosta-Martínez, Maricedes
Publicado: (2012)

PI3K/AKT/mTOR Pathway in Angiogenesis
por: Karar, Jayashree, et al.
Publicado: (2011)

Modulation of telomere protection by the PI3K/AKT pathway
por: Méndez-Pertuz, Marinela, et al.
Publicado: (2017)

The effects of Ginsenosides on PI3K/AKT signaling pathway
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2022)

Applications of spatially resolved omics in the field of endocrine tumors
por: Hou, Yinuo, et al.
Publicado: (2023)

Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway
por: Li, Bin, et al.
Publicado: (2014)

Editorial: DNA damage response pathways meet endocrine systems
por: Werner, Haim, et al.
Publicado: (2023)

Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092
por: Yu, Yi, et al.
Publicado: (2015)

Endocrine Disrupting Chemicals: Effects on Endocrine Glands
por: Lauretta, Rosa, et al.
Publicado: (2019)

Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells
por: TIAN, FENG, et al.
Publicado: (2015)

Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells
por: Tian, Feng, et al.
Publicado: (2023)

The Tumor Microenvironment as a Regulator of Endocrine Resistance in Breast Cancer
por: Diaz Bessone, María Inés, et al.
Publicado: (2019)

Phakomatoses and Endocrine Gland Tumors: Noteworthy and (Not so) Rare Associations
por: Chevalier, Benjamin, et al.
Publicado: (2021)

Activation of the PI3K/AKT Pathway in Merkel Cell Carcinoma
por: Hafner, Christian, et al.
Publicado: (2012)

The multi-faceted roles of the PI3K-AKT pathway in melanoma
por: Davies, Michael A
Publicado: (2015)

Expression quantitative trait loci for PI3K/AKT pathway
por: Ryu, Dongchan, et al.
Publicado: (2017)

Necessity to evaluate PI3K/Akt signalling pathway in proarrhythmia
por: Ezeani, Martin, et al.
Publicado: (2017)

The PI3K/AKT pathway in obesity and type 2 diabetes
por: Huang, Xingjun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_eba93lcu3sqql4529pgech0g3e