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Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy
HIV infection profoundly affects many parameters of the immune system and ultimately leads to AIDS, yet which factors are most important for determining resistance, pathology, and response to antiretroviral treatment – and how best to monitor them – remain unclear. We develop a quantitative high-thr...
Autores principales: | Heather, James M., Best, Katharine, Oakes, Theres, Gray, Eleanor R., Roe, Jennifer K., Thomas, Niclas, Friedman, Nir, Noursadeghi, Mahdad, Chain, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707277/ https://www.ncbi.nlm.nih.gov/pubmed/26793190 http://dx.doi.org/10.3389/fimmu.2015.00644 |
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