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Iron-Mediated Lysosomal Membrane Permeabilization in Ethanol-Induced Hepatic Oxidative Damage and Apoptosis: Protective Effects of Quercetin

Iron, in its free ferrous states, can catalyze Fenton reaction to produce OH∙, which is recognized as a crucial role in the pathogenesis of alcoholic liver diseases (ALD). As a result of continuous decomposition of iron-containing compounds, lysosomes contain a pool of redox-active iron. To investig...

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Detalles Bibliográficos
Autores principales:	Li, Yanyan, Chen, Man, Xu, Yanyan, Yu, Xiao, Xiong, Ting, Du, Min, Sun, Jian, Liu, Liegang, Tang, Yuhan, Yao, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707336/ https://www.ncbi.nlm.nih.gov/pubmed/27057276 http://dx.doi.org/10.1155/2016/4147610

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