Cargando…
The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells
Structural and biochemical alterations of the microtubule-associated protein tau (MAPT) are associated with degenerative disorders referred to as tauopathies. We have previously shown that MAPT is present in human islets of Langerhans, human insulinomas, and pancreatic beta-cell line models, with bi...
Autores principales: | Maj, Magdalena, Hoermann, Gregor, Rasul, Sazan, Base, Wolfgang, Wagner, Ludwig, Attems, Johannes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707345/ https://www.ncbi.nlm.nih.gov/pubmed/26824039 http://dx.doi.org/10.1155/2016/1964634 |
Ejemplares similares
-
Dynamic 2-deoxy-2[18F] fluoro-D-glucose PET/MRI in human renal allotransplant patients undergoing acute kidney injury
por: Pajenda, Sahra, et al.
Publicado: (2020) -
Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity
por: Gorsky, Marianna Karina, et al.
Publicado: (2017) -
Microtubule-binding core of the tau protein
por: El Mammeri, Nadia, et al.
Publicado: (2022) -
Cysteine residues in signal transduction and its relevance in pancreatic beta cells
por: Holendova, Blanka, et al.
Publicado: (2023) -
Partial mimicry of the microtubule binding of tau by its membrane binding
por: MacAinsh, Matthew, et al.
Publicado: (2023)