Mutation-Specific Phenotypes in hiPSC-Derived Cardiomyocytes Carrying Either Myosin-Binding Protein C Or α-Tropomyosin Mutation for Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disease, which affects the structure of heart muscle tissue. The clinical symptoms include arrhythmias, progressive heart failure, and even sudden cardiac death but the mutation carrier can also be totally asymptomatic. To date, over 1400 mutati...

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Detalles Bibliográficos
Autores principales: Ojala, Marisa, Prajapati, Chandra, Pölönen, Risto-Pekka, Rajala, Kristiina, Pekkanen-Mattila, Mari, Rasku, Jyrki, Larsson, Kim, Aalto-Setälä, Katriina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707351/
https://www.ncbi.nlm.nih.gov/pubmed/27057166
http://dx.doi.org/10.1155/2016/1684792

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