Modulation of Hydrogen Peroxide-Induced Oxidative Stress in Human Neuronal Cells by Thymoquinone-Rich Fraction and Thymoquinone via Transcriptomic Regulation of Antioxidant and Apoptotic Signaling Genes

Nigella sativa Linn. (N. sativa) and its bioactive constituent Thymoquinone (TQ) have demonstrated numerous pharmacological attributes. In the present study, the neuroprotective properties of Thymoquinone-rich fraction (TQRF) and TQ against hydrogen peroxide- (H(2)O(2)-) induced neurotoxicity in dif...

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Detalles Bibliográficos
Autores principales: Ismail, Norsharina, Ismail, Maznah, Azmi, Nur Hanisah, Abu Bakar, Muhammad Firdaus, Basri, Hamidon, Abdullah, Maizaton Atmadini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707358/
https://www.ncbi.nlm.nih.gov/pubmed/26823946
http://dx.doi.org/10.1155/2016/2528935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707358/
https://www.ncbi.nlm.nih.gov/pubmed/26823946
http://dx.doi.org/10.1155/2016/2528935

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