A human monoclonal antibody against HPV16 recognizes an immunodominant and neutralizing epitope partially overlapping with that of H16.V5

The presence of neutralizing epitopes in human papillomavirus (HPV) L1 virus-like particles (VLPs) is the structural basis of prophylactic vaccines. An anti-HPV16 neutralizing monoclonal antibody (N-mAb) 26D1 was isolated from a memory B cell of a human vaccinee. The pre-binding of heparan sulfate t...

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Detalles Bibliográficos
Autores principales: Xia, Lin, Xian, Yangfei, Wang, Daning, Chen, Yuanzhi, Huang, Xiaofen, Bi, Xingjian, Yu, Hai, Fu, Zheng, Liu, Xinlin, Li, Shaowei, An, Zhiqiang, Luo, Wenxin, Zhao, Qinjian, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707464/
https://www.ncbi.nlm.nih.gov/pubmed/26750243
http://dx.doi.org/10.1038/srep19042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707464/
https://www.ncbi.nlm.nih.gov/pubmed/26750243
http://dx.doi.org/10.1038/srep19042

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