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Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination

Steroidogenic factor 1 (SF-1) is a transcription factor expressed in the ventral medial nucleus of the hypothalamus that regulates energy homeostasis. However, the molecular mechanisms of SF-1 in the control of energy balance are largely unknown. Here, we show that nutritional conditions, such as th...

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Detalles Bibliográficos
Autores principales:	Lee, Jiwon, Yang, Dong Joo, Lee, Syann, Hammer, Gary D., Kim, Ki Woo, Elmquist, Joel K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707483/ https://www.ncbi.nlm.nih.gov/pubmed/26750456 http://dx.doi.org/10.1038/srep19143

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