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OASL1 deficiency promotes antiviral protection against genital herpes simplex virus type 2 infection by enhancing type I interferon production

Type I interferon (IFN) interferes with virus replication, promotes antiviral responses, and controls innate and adaptive immune responses to certain viruses. Recently, we reported that 2’–5’ oligoadenylate synthetase-like 1 (OASL1) negatively regulates type I IFN production by inhibiting the transl...

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Detalles Bibliográficos
Autores principales:	Oh, Ji Eun, Lee, Myeong Sup, Kim, Young-Joon, Lee, Heung Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707503/ https://www.ncbi.nlm.nih.gov/pubmed/26750802 http://dx.doi.org/10.1038/srep19089

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