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Lubricin/Proteoglycan 4 binds to and regulates the activity of Toll-Like Receptors In Vitro
Proteoglycan 4 (PRG4/lubricin) is secreted by cells that reside in articular cartilage and line the synovial joint. Lubricin may play a role in modulating inflammatory responses through interaction with CD44. This led us to examine if lubricin could be playing a larger role in the modulation of infl...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707532/ https://www.ncbi.nlm.nih.gov/pubmed/26752378 http://dx.doi.org/10.1038/srep18910 |