Lubricin/Proteoglycan 4 binds to and regulates the activity of Toll-Like Receptors In Vitro

Proteoglycan 4 (PRG4/lubricin) is secreted by cells that reside in articular cartilage and line the synovial joint. Lubricin may play a role in modulating inflammatory responses through interaction with CD44. This led us to examine if lubricin could be playing a larger role in the modulation of infl...

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Detalles Bibliográficos
Autores principales: Iqbal, S.M., Leonard, C., C. Regmi, S., De Rantere, D., Tailor, P., Ren, G., Ishida, H., Hsu, CY., Abubacker, S., Pang, D. SJ., T. Salo, P., Vogel, H.J., Hart, D.A., Waterhouse, C.C., Jay, G.D, Schmidt, T.A., Krawetz, R.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707532/
https://www.ncbi.nlm.nih.gov/pubmed/26752378
http://dx.doi.org/10.1038/srep18910

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