LEGO: a novel method for gene set over-representation analysis by incorporating network-based gene weights

Pathway or gene set over-representation analysis (ORA) has become a routine task in functional genomics studies. However, currently widely used ORA tools employ statistical methods such as Fisher’s exact test that reduce a pathway into a list of genes, ignoring the constitutive functional non-equiva...

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Detalles Bibliográficos
Autores principales: Dong, Xinran, Hao, Yun, Wang, Xiao, Tian, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707541/
https://www.ncbi.nlm.nih.gov/pubmed/26750448
http://dx.doi.org/10.1038/srep18871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707541/
https://www.ncbi.nlm.nih.gov/pubmed/26750448
http://dx.doi.org/10.1038/srep18871

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