Evolution of the immune system in humans from infancy to old age

This article reviews the development of the immune response through neonatal, infant and adult life, including pregnancy, ending with the decline in old age. A picture emerges of a child born with an immature, innate and adaptive immune system, which matures and acquires memory as he or she grows. I...

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Detalles Bibliográficos
Autores principales: Simon, A. Katharina, Hollander, Georg A., McMichael, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Special Feature
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707740/
https://www.ncbi.nlm.nih.gov/pubmed/26702035
http://dx.doi.org/10.1098/rspb.2014.3085
Descripción
Sumario:This article reviews the development of the immune response through neonatal, infant and adult life, including pregnancy, ending with the decline in old age. A picture emerges of a child born with an immature, innate and adaptive immune system, which matures and acquires memory as he or she grows. It then goes into decline in old age. These changes are considered alongside the risks of different types of infection, autoimmune disease and malignancy.

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