Evolution of the immune system in humans from infancy to old age

This article reviews the development of the immune response through neonatal, infant and adult life, including pregnancy, ending with the decline in old age. A picture emerges of a child born with an immature, innate and adaptive immune system, which matures and acquires memory as he or she grows. I...

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Detalles Bibliográficos
Autores principales: Simon, A. Katharina, Hollander, Georg A., McMichael, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Special Feature
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707740/
https://www.ncbi.nlm.nih.gov/pubmed/26702035
http://dx.doi.org/10.1098/rspb.2014.3085
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author Simon, A. Katharina
Hollander, Georg A.
McMichael, Andrew
author_facet Simon, A. Katharina
Hollander, Georg A.
McMichael, Andrew
author_sort Simon, A. Katharina
collection PubMed
description This article reviews the development of the immune response through neonatal, infant and adult life, including pregnancy, ending with the decline in old age. A picture emerges of a child born with an immature, innate and adaptive immune system, which matures and acquires memory as he or she grows. It then goes into decline in old age. These changes are considered alongside the risks of different types of infection, autoimmune disease and malignancy.
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spelling pubmed-47077402016-01-26 Evolution of the immune system in humans from infancy to old age Simon, A. Katharina Hollander, Georg A. McMichael, Andrew Proc Biol Sci Special Feature This article reviews the development of the immune response through neonatal, infant and adult life, including pregnancy, ending with the decline in old age. A picture emerges of a child born with an immature, innate and adaptive immune system, which matures and acquires memory as he or she grows. It then goes into decline in old age. These changes are considered alongside the risks of different types of infection, autoimmune disease and malignancy. The Royal Society 2015-12-22 /pmc/articles/PMC4707740/ /pubmed/26702035 http://dx.doi.org/10.1098/rspb.2014.3085 Text en © 2015 The Authors. http://creativecommons.org/licenses/by/4.0/ © 2015 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Special Feature
Simon, A. Katharina
Hollander, Georg A.
McMichael, Andrew
Evolution of the immune system in humans from infancy to old age
title Evolution of the immune system in humans from infancy to old age
title_full Evolution of the immune system in humans from infancy to old age
title_fullStr Evolution of the immune system in humans from infancy to old age
title_full_unstemmed Evolution of the immune system in humans from infancy to old age
title_short Evolution of the immune system in humans from infancy to old age
title_sort evolution of the immune system in humans from infancy to old age
topic Special Feature
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707740/
https://www.ncbi.nlm.nih.gov/pubmed/26702035
http://dx.doi.org/10.1098/rspb.2014.3085
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AT mcmichaelandrew evolutionoftheimmunesysteminhumansfrominfancytooldage

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