Cargando…
Biochemical studies on Francisella tularensis RelA in (p)ppGpp biosynthesis
The bacterial stringent response is induced by nutrient deprivation and is mediated by enzymes of the RSH (RelA/SpoT homologue; RelA, (p)ppGpp synthetase I; SpoT, (p)ppGpp synthetase II) superfamily that control concentrations of the ‘alarmones’ (p)ppGpp (guanosine penta- or tetra-phosphate). This r...
Autores principales: | Wilkinson, Rachael C., Batten, Laura E., Wells, Neil J., Oyston, Petra C.F., Roach, Peter L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708007/ https://www.ncbi.nlm.nih.gov/pubmed/26450927 http://dx.doi.org/10.1042/BSR20150229 |
Ejemplares similares
-
Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor
por: Beljantseva, Jelena, et al.
Publicado: (2017) -
6S RNA regulation of relA alters ppGpp levels in early stationary phase
por: Cavanagh, Amy T., et al.
Publicado: (2010) -
The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis
por: Arenz, Stefan, et al.
Publicado: (2016) -
The RelA hydrolase domain acts as a molecular switch for (p)ppGpp synthesis
por: Sinha, Anurag Kumar, et al.
Publicado: (2021) -
The roles of RelA/(p)ppGpp in glucose-starvation induced adaptive response in the zoonotic Streptococcus suis
por: Zhang, Tengfei, et al.
Publicado: (2016)