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DNA prime-protein boost based vaccination with a conserved region of leptospiral immunoglobulin-like A and B proteins enhances protection against leptospirosis

Leptospirosis is a zoonotic disease caused by pathogenic spirochetes of theLeptospira genus. Vaccination with bacterins has severe limitations. Here, we evaluated the N-terminal region of the leptospiral immunoglobulin-like B protein (LigBrep) as a vaccine candidate against leptospirosis using immun...

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Detalles Bibliográficos
Autores principales:	Forster, Karine M, Hartwig, Daiane D, Oliveira, Thaís L, Bacelo, Kátia L, Schuch, Rodrigo, Amaral, Marta G, Dellagostin, Odir A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708018/ https://www.ncbi.nlm.nih.gov/pubmed/26676320 http://dx.doi.org/10.1590/0074-02760150222

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