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JEPEGMIX: gene-level joint analysis of functional SNPs in cosmopolitan cohorts
Motivation: To increase detection power, gene level analysis methods are used to aggregate weak signals. To greatly increase computational efficiency, most methods use as input summary statistics from genome-wide association studies (GWAS). Subsequently, gene statistics are constructed using linkage...
Autores principales: | Lee, Donghyung, Williamson, Vernell S., Bigdeli, T. Bernard, Riley, Brien P., Webb, Bradley T., Fanous, Ayman H., Kendler, Kenneth S., Vladimirov, Vladimir I., Bacanu, Silviu-Alin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708106/ https://www.ncbi.nlm.nih.gov/pubmed/26428293 http://dx.doi.org/10.1093/bioinformatics/btv567 |
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