Cancer stem cells in prostate cancer

Prostate cancer (P-Ca) remains a leading cause of cancer-related death in men. Lately, increasing evidence for a hierarchically organized cancer stem cell (CSC) model emerged for different tumors entities, including P-Ca. CSCs are defined by several characteristics including self-renewal, pluripoten...

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Detalles Bibliográficos
Autores principales: Moltzahn, Felix, Thalmann, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708185/
https://www.ncbi.nlm.nih.gov/pubmed/26816738
http://dx.doi.org/10.3978/j.issn.2223-4683.2013.09.06
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author Moltzahn, Felix
Thalmann, George N.
author_facet Moltzahn, Felix
Thalmann, George N.
author_sort Moltzahn, Felix
collection PubMed
description Prostate cancer (P-Ca) remains a leading cause of cancer-related death in men. Lately, increasing evidence for a hierarchically organized cancer stem cell (CSC) model emerged for different tumors entities, including P-Ca. CSCs are defined by several characteristics including self-renewal, pluripotency and tumorigenicity and are thought to be responsible for tumor recurrence, metastasis and cancer related death. In this review we discuss the recent research in the field of CSCs, its limitations and therapeutical implications in general and specifically in P-Ca.
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spelling pubmed-47081852016-01-26 Cancer stem cells in prostate cancer Moltzahn, Felix Thalmann, George N. Transl Androl Urol Review Article Prostate cancer (P-Ca) remains a leading cause of cancer-related death in men. Lately, increasing evidence for a hierarchically organized cancer stem cell (CSC) model emerged for different tumors entities, including P-Ca. CSCs are defined by several characteristics including self-renewal, pluripotency and tumorigenicity and are thought to be responsible for tumor recurrence, metastasis and cancer related death. In this review we discuss the recent research in the field of CSCs, its limitations and therapeutical implications in general and specifically in P-Ca. AME Publishing Company 2013-09 /pmc/articles/PMC4708185/ /pubmed/26816738 http://dx.doi.org/10.3978/j.issn.2223-4683.2013.09.06 Text en 2013 Translational Andrology and Urology. All rights reserved.
spellingShingle Review Article
Moltzahn, Felix
Thalmann, George N.
Cancer stem cells in prostate cancer
title Cancer stem cells in prostate cancer
title_full Cancer stem cells in prostate cancer
title_fullStr Cancer stem cells in prostate cancer
title_full_unstemmed Cancer stem cells in prostate cancer
title_short Cancer stem cells in prostate cancer
title_sort cancer stem cells in prostate cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708185/
https://www.ncbi.nlm.nih.gov/pubmed/26816738
http://dx.doi.org/10.3978/j.issn.2223-4683.2013.09.06
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