Baicalein attenuates the quorum sensing-controlled virulence factors of Pseudomonas aeruginosa and relieves the inflammatory response in P. aeruginosa-infected macrophages by downregulating the MAPK and NFκB signal-transduction pathways

Burgeoning antibiotic resistance and unfavorable outcomes of inflammatory injury after Pseudomonas aeruginosa infection have necessitated the development of novel agents that not only target quorum sensing (QS) but also combat inflammatory injury with the least risk of resistance. This study aimed t...

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Detalles Bibliográficos
Autores principales: Luo, Jing, Kong, Jin-liang, Dong, Bi-ying, Huang, Hong, Wang, Ke, Wu, Li-hong, Hou, Chang-chun, Liang, Yue, Li, Bing, Chen, Yi-qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708194/
https://www.ncbi.nlm.nih.gov/pubmed/26792984
http://dx.doi.org/10.2147/DDDT.S97221

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