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Advances in the treatment of testicular cancer
Germ cell tumors (GCT) are relatively uncommon, accounting for only 1% of male malignancies in the United States. It has become an important oncological disease for several reasons. It is the most common malignancy in young men 15-35 years old. GCTs are among a unique numbers of neoplasms where bioc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708227/ https://www.ncbi.nlm.nih.gov/pubmed/26816836 http://dx.doi.org/10.3978/j.issn.2223-4683.2015.06.02 |
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author | Ehrlich, Yaron Margel, David Lubin, Marc Alan Baniel, Jack |
author_facet | Ehrlich, Yaron Margel, David Lubin, Marc Alan Baniel, Jack |
author_sort | Ehrlich, Yaron |
collection | PubMed |
description | Germ cell tumors (GCT) are relatively uncommon, accounting for only 1% of male malignancies in the United States. It has become an important oncological disease for several reasons. It is the most common malignancy in young men 15-35 years old. GCTs are among a unique numbers of neoplasms where biochemical markers play a critical role. Finally, it is a model of curable cancer. In this review we discuss cancer epidemiology, genetics, and therapeutic principles. Recent advances in the management of stage I GCT and controversies in the management of post chemotherapy residual mass are presented. |
format | Online Article Text |
id | pubmed-4708227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-47082272016-01-26 Advances in the treatment of testicular cancer Ehrlich, Yaron Margel, David Lubin, Marc Alan Baniel, Jack Transl Androl Urol Review Article Germ cell tumors (GCT) are relatively uncommon, accounting for only 1% of male malignancies in the United States. It has become an important oncological disease for several reasons. It is the most common malignancy in young men 15-35 years old. GCTs are among a unique numbers of neoplasms where biochemical markers play a critical role. Finally, it is a model of curable cancer. In this review we discuss cancer epidemiology, genetics, and therapeutic principles. Recent advances in the management of stage I GCT and controversies in the management of post chemotherapy residual mass are presented. AME Publishing Company 2015-06 /pmc/articles/PMC4708227/ /pubmed/26816836 http://dx.doi.org/10.3978/j.issn.2223-4683.2015.06.02 Text en 2015 Translational Andrology and Urology. All rights reserved. |
spellingShingle | Review Article Ehrlich, Yaron Margel, David Lubin, Marc Alan Baniel, Jack Advances in the treatment of testicular cancer |
title | Advances in the treatment of testicular cancer |
title_full | Advances in the treatment of testicular cancer |
title_fullStr | Advances in the treatment of testicular cancer |
title_full_unstemmed | Advances in the treatment of testicular cancer |
title_short | Advances in the treatment of testicular cancer |
title_sort | advances in the treatment of testicular cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708227/ https://www.ncbi.nlm.nih.gov/pubmed/26816836 http://dx.doi.org/10.3978/j.issn.2223-4683.2015.06.02 |
work_keys_str_mv | AT ehrlichyaron advancesinthetreatmentoftesticularcancer AT margeldavid advancesinthetreatmentoftesticularcancer AT lubinmarcalan advancesinthetreatmentoftesticularcancer AT banieljack advancesinthetreatmentoftesticularcancer |