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AB198. Nodal regulates the differentiation of iPS cells to male germ cells via Smad2/3, Oct4 and Foxh1 activation
OBJECTIVE: The differentiation of male germ cells from iPS cells provides an ideal model for unveiling molecular mechanisms of spermatogenesis. Nodal could promote proliferation of mouse spermatogonial stem/progenitor cells via Smad2/3 and oct-4 activation. The objective of this study was to determi...
Autores principales: | Yang, Shi, Tian, Ruhui, Wang, Junlong, Zhu, Zijue, Li, Peng, Li, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708306/ http://dx.doi.org/10.3978/j.issn.2223-4683.2014.s198 |
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