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AB228. Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells

Lysosomes are acidic organelles that have a crucial role in degrading intracellular macromolecules and organelles during the final stage of autophagy. Tetrandrine (Tet), a bisbenzylisoquinoline alkaloid, was reported as an autophagy activator. Here, in contrast with previous studies, we show that Te...

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Detalles Bibliográficos
Autores principales: Qiu, Wei, Guan, Ruili, He, Wei, Gong, Yanqing, Guo, Yinglu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708505/
http://dx.doi.org/10.3978/j.issn.2223-4683.2014.s228

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