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AB037. Role of nocturnal penile erection test on response to daily sildenafil in patients with erectile dysfunction due to pelvic fracture urethral disruption

OBJECTIVE: To evaluate the results of nocturnal penile erection test and response to daily sildenafil in patients with erectile dysfunction (ED) due to pelvic fracture urethral disruption. METHODS: In the past three years, we included 38 patients with ED due to pelvic fracture urethral disruption. T...

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Detalles Bibliográficos
Autores principales: Lin, Jian, Peng, Jing, Zhang, Zhichao, Cui, Wanshou, Yuan, Yiming, Gao, Bing, Song, Weidong, Tang, Yan, Xin, Zhongcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708841/
http://dx.doi.org/10.3978/j.issn.2223-4683.2015.s037
Descripción
Sumario:OBJECTIVE: To evaluate the results of nocturnal penile erection test and response to daily sildenafil in patients with erectile dysfunction (ED) due to pelvic fracture urethral disruption. METHODS: In the past three years, we included 38 patients with ED due to pelvic fracture urethral disruption. The mean age was 33.1 years (range, 22-49 years). All were evaluated subjectively and objectively by the International Index of Erectile Function-5, nocturnal penile tumescence and rigidity (NPTR) test, and penile Doppler ultrasonography. Patients received daily sildenafil 50 mg for 3 months. RESULTS: Thirty-one patients were followed up: 54.8% showed response to sildenafil defined as reporting successful vaginal penetration and intercourse. Patients with neurogenic, arterial, and venous EDs did not differ in efficiency rates (P ¼ .587). However, the penile erectile rigidity recorded by NPTR test affected efficiency significantly (P ¼ .046). Patients with tip rigidity >40% had the highest response rate (76.9%), but the response rate for patients with tip rigidity <20% was only 22.2%. CONCLUSIONS: NPTR recording can reveal resident erectile function in patients with ED due to trauma and is significant for selecting pharmacologic treatment as optimal therapy.