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Epidemiological study of soft‐tissue sarcomas in Ireland

Soft‐tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements. The aim of this paper is to describe the current incidence and survival of STS from 1994 to 2012 in Ireland and compare these with...

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Autores principales: Bhatt, Nikita, Deady, Sandra, Gillis, Amy, Bertuzzi, Alexia, Fabre, Aurelie, Heffernan, Eric, Gillham, Charles, O'Toole, Gary, Ridgway, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708898/
https://www.ncbi.nlm.nih.gov/pubmed/26589778
http://dx.doi.org/10.1002/cam4.547
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author Bhatt, Nikita
Deady, Sandra
Gillis, Amy
Bertuzzi, Alexia
Fabre, Aurelie
Heffernan, Eric
Gillham, Charles
O'Toole, Gary
Ridgway, Paul F.
author_facet Bhatt, Nikita
Deady, Sandra
Gillis, Amy
Bertuzzi, Alexia
Fabre, Aurelie
Heffernan, Eric
Gillham, Charles
O'Toole, Gary
Ridgway, Paul F.
author_sort Bhatt, Nikita
collection PubMed
description Soft‐tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements. The aim of this paper is to describe the current incidence and survival of STS from 1994 to 2012 in Ireland and compare these with comparably coded international published reports. This is a retrospective, population study based on the data from the National Cancer Registry of Ireland (NCRI). Incidence and relative survival rates for STS in Ireland were generated. Incidence of STS based on gender, age and anatomical location was examined. Annual mean incidence rate (European Age Standardized) in Ireland between 1994 and 2012 was 4.48 ± 0.15 per 100,000 person‐years. The overall relative 5‐year survival rate of STS for the period 1994–2011 in Ireland was 56%, which was similar to that reported in the U.K. but lower than in most of Europe and U.S.A. Survival rate fluctuated over the period examined, declining slightly in females but showing an increase in males. STS incidence trends in Ireland were comparable to international reports. Survival trends of STS were significantly different between Ireland and other European countries, requiring further study to understand causation.
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spelling pubmed-47088982016-01-19 Epidemiological study of soft‐tissue sarcomas in Ireland Bhatt, Nikita Deady, Sandra Gillis, Amy Bertuzzi, Alexia Fabre, Aurelie Heffernan, Eric Gillham, Charles O'Toole, Gary Ridgway, Paul F. Cancer Med Cancer Prevention Soft‐tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements. The aim of this paper is to describe the current incidence and survival of STS from 1994 to 2012 in Ireland and compare these with comparably coded international published reports. This is a retrospective, population study based on the data from the National Cancer Registry of Ireland (NCRI). Incidence and relative survival rates for STS in Ireland were generated. Incidence of STS based on gender, age and anatomical location was examined. Annual mean incidence rate (European Age Standardized) in Ireland between 1994 and 2012 was 4.48 ± 0.15 per 100,000 person‐years. The overall relative 5‐year survival rate of STS for the period 1994–2011 in Ireland was 56%, which was similar to that reported in the U.K. but lower than in most of Europe and U.S.A. Survival rate fluctuated over the period examined, declining slightly in females but showing an increase in males. STS incidence trends in Ireland were comparable to international reports. Survival trends of STS were significantly different between Ireland and other European countries, requiring further study to understand causation. John Wiley and Sons Inc. 2015-11-21 /pmc/articles/PMC4708898/ /pubmed/26589778 http://dx.doi.org/10.1002/cam4.547 Text en © 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cancer Prevention
Bhatt, Nikita
Deady, Sandra
Gillis, Amy
Bertuzzi, Alexia
Fabre, Aurelie
Heffernan, Eric
Gillham, Charles
O'Toole, Gary
Ridgway, Paul F.
Epidemiological study of soft‐tissue sarcomas in Ireland
title Epidemiological study of soft‐tissue sarcomas in Ireland
title_full Epidemiological study of soft‐tissue sarcomas in Ireland
title_fullStr Epidemiological study of soft‐tissue sarcomas in Ireland
title_full_unstemmed Epidemiological study of soft‐tissue sarcomas in Ireland
title_short Epidemiological study of soft‐tissue sarcomas in Ireland
title_sort epidemiological study of soft‐tissue sarcomas in ireland
topic Cancer Prevention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708898/
https://www.ncbi.nlm.nih.gov/pubmed/26589778
http://dx.doi.org/10.1002/cam4.547
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