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Epidemiological study of soft‐tissue sarcomas in Ireland
Soft‐tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements. The aim of this paper is to describe the current incidence and survival of STS from 1994 to 2012 in Ireland and compare these with...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708898/ https://www.ncbi.nlm.nih.gov/pubmed/26589778 http://dx.doi.org/10.1002/cam4.547 |
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author | Bhatt, Nikita Deady, Sandra Gillis, Amy Bertuzzi, Alexia Fabre, Aurelie Heffernan, Eric Gillham, Charles O'Toole, Gary Ridgway, Paul F. |
author_facet | Bhatt, Nikita Deady, Sandra Gillis, Amy Bertuzzi, Alexia Fabre, Aurelie Heffernan, Eric Gillham, Charles O'Toole, Gary Ridgway, Paul F. |
author_sort | Bhatt, Nikita |
collection | PubMed |
description | Soft‐tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements. The aim of this paper is to describe the current incidence and survival of STS from 1994 to 2012 in Ireland and compare these with comparably coded international published reports. This is a retrospective, population study based on the data from the National Cancer Registry of Ireland (NCRI). Incidence and relative survival rates for STS in Ireland were generated. Incidence of STS based on gender, age and anatomical location was examined. Annual mean incidence rate (European Age Standardized) in Ireland between 1994 and 2012 was 4.48 ± 0.15 per 100,000 person‐years. The overall relative 5‐year survival rate of STS for the period 1994–2011 in Ireland was 56%, which was similar to that reported in the U.K. but lower than in most of Europe and U.S.A. Survival rate fluctuated over the period examined, declining slightly in females but showing an increase in males. STS incidence trends in Ireland were comparable to international reports. Survival trends of STS were significantly different between Ireland and other European countries, requiring further study to understand causation. |
format | Online Article Text |
id | pubmed-4708898 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-47088982016-01-19 Epidemiological study of soft‐tissue sarcomas in Ireland Bhatt, Nikita Deady, Sandra Gillis, Amy Bertuzzi, Alexia Fabre, Aurelie Heffernan, Eric Gillham, Charles O'Toole, Gary Ridgway, Paul F. Cancer Med Cancer Prevention Soft‐tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements. The aim of this paper is to describe the current incidence and survival of STS from 1994 to 2012 in Ireland and compare these with comparably coded international published reports. This is a retrospective, population study based on the data from the National Cancer Registry of Ireland (NCRI). Incidence and relative survival rates for STS in Ireland were generated. Incidence of STS based on gender, age and anatomical location was examined. Annual mean incidence rate (European Age Standardized) in Ireland between 1994 and 2012 was 4.48 ± 0.15 per 100,000 person‐years. The overall relative 5‐year survival rate of STS for the period 1994–2011 in Ireland was 56%, which was similar to that reported in the U.K. but lower than in most of Europe and U.S.A. Survival rate fluctuated over the period examined, declining slightly in females but showing an increase in males. STS incidence trends in Ireland were comparable to international reports. Survival trends of STS were significantly different between Ireland and other European countries, requiring further study to understand causation. John Wiley and Sons Inc. 2015-11-21 /pmc/articles/PMC4708898/ /pubmed/26589778 http://dx.doi.org/10.1002/cam4.547 Text en © 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Cancer Prevention Bhatt, Nikita Deady, Sandra Gillis, Amy Bertuzzi, Alexia Fabre, Aurelie Heffernan, Eric Gillham, Charles O'Toole, Gary Ridgway, Paul F. Epidemiological study of soft‐tissue sarcomas in Ireland |
title | Epidemiological study of soft‐tissue sarcomas in Ireland |
title_full | Epidemiological study of soft‐tissue sarcomas in Ireland |
title_fullStr | Epidemiological study of soft‐tissue sarcomas in Ireland |
title_full_unstemmed | Epidemiological study of soft‐tissue sarcomas in Ireland |
title_short | Epidemiological study of soft‐tissue sarcomas in Ireland |
title_sort | epidemiological study of soft‐tissue sarcomas in ireland |
topic | Cancer Prevention |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708898/ https://www.ncbi.nlm.nih.gov/pubmed/26589778 http://dx.doi.org/10.1002/cam4.547 |
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