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Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde
Cinnamomum verum is used to make the spice cinnamon and has been used as a traditional Chinese herbal medicine for various applications. We evaluated the anticancer effect of 2-methoxycinnamaldehyde (2-MCA), a constituent of the bark of the plant, and its underlying molecular biomarkers associated w...
Autores principales: | Perng, Daw-Shyong, Tsai, Yu-Hsin, Cherng, Jonathan, Wang, Jeng-Shing, Chou, Kuo-Shen, Shih, Chia-Wen, Cherng, Jaw-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708962/ https://www.ncbi.nlm.nih.gov/pubmed/26792981 http://dx.doi.org/10.2147/DDDT.S93599 |
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