Cargando…
Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus K(d)M2(82-90) Epitope Is Transfer Dose-Dependent
In this study, we compared two lines of transgenic CD8+ T cells specific for the same K(d)M2(82-90) epitope of respiratory syncytial virus in the CB6F1 hybrid mouse model. Here we found that these two transgenic lines had similar in vivo abilities to control viral load after respiratory syncytial vi...
Autores principales: | Morabito, Kaitlyn M., Erez, Noam, Graham, Barney S., Ruckwardt, Tracy J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708989/ https://www.ncbi.nlm.nih.gov/pubmed/26752171 http://dx.doi.org/10.1371/journal.pone.0146781 |
Ejemplares similares
-
CD8+ TCR Transgenic Strains Expressing Public versus Private TCR Targeting the Respiratory Syncytial Virus K(d)M2(82–90) Epitope Demonstrate Similar Functional Profiles
por: Bar-Haim, Erez, et al.
Publicado: (2014) -
Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103+ dendritic cell populations following respiratory infection
por: Ruckwardt, Tracy J, et al.
Publicado: (2017) -
Neonatal CD8 T-cell Hierarchy Is Distinct from Adults and Is Influenced by Intrinsic T cell Properties in Respiratory Syncytial Virus Infected Mice
por: Ruckwardt, Tracy J., et al.
Publicado: (2011) -
Quantitative and Qualitative Deficits in Neonatal Lung-Migratory Dendritic Cells Impact the Generation of the CD8+ T Cell Response
por: Ruckwardt, Tracy J., et al.
Publicado: (2014) -
Epitope-Specific Serological Assays for RSV: Conformation Matters
por: Phung, Emily, et al.
Publicado: (2019)