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Increased Skin Tumor Incidence and Keratinocyte Hyper-Proliferation in a Mouse Model of Down Syndrome

Down syndrome (DS) is a genetic disorder caused by the presence of an extra copy of human chromosome 21 (Hsa21). People with DS display multiple clinical traits as a result of the dosage imbalance of several hundred genes. While many outcomes of trisomy are deleterious, epidemiological studies have...

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Detalles Bibliográficos
Autores principales:	Yang, Annan, Currier, Duane, Poitras, Jennifer L., Reeves, Roger H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708994/ https://www.ncbi.nlm.nih.gov/pubmed/26752700 http://dx.doi.org/10.1371/journal.pone.0146570

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