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Using Linkage Analysis to Detect Gene-Gene Interactions. 2. Improved Reliability and Extension to More-Complex Models

Detecting gene-gene interaction in complex diseases has become an important priority for common disease genetics, but most current approaches to detecting interaction start with disease-marker associations. These approaches are based on population allele frequency correlations, not genetic inheritan...

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Detalles Bibliográficos
Autores principales: Hodge, Susan E., Hager, Valerie R., Greenberg, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709060/
https://www.ncbi.nlm.nih.gov/pubmed/26752287
http://dx.doi.org/10.1371/journal.pone.0146240