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A trans-acting Variant within the Transcription Factor RIM101 Interacts with Genetic Background to Determine its Regulatory Capacity

Most genetic variants associated with disease occur within regulatory regions of the genome, underscoring the importance of defining the mechanisms underlying differences in regulation of gene expression between individuals. We discovered a pair of co-regulated, divergently oriented transcripts, AQY...

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Detalles Bibliográficos
Autores principales: Read, Timothy, Richmond, Phillip A., Dowell, Robin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709078/
https://www.ncbi.nlm.nih.gov/pubmed/26751950
http://dx.doi.org/10.1371/journal.pgen.1005746