Ultra-Deep Bisulfite Sequencing to Detect Specific DNA Methylation Patterns of Minor Cell Types in Heterogeneous Cell Populations: An Example of the Pituitary Tissue

DNA methylation is an epigenetic modification important for cell fate determination and cell type-specific gene expression. Transcriptional regulatory regions of the mammalian genome contain a large number of tissue/cell type-dependent differentially methylated regions (T-DMRs) with DNA methylation...

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Detalles Bibliográficos
Autores principales: Arai, Yoshikazu, Fukukawa, Hisho, Atozi, Takanori, Matsumoto, Shoma, Hanazono, Yutaka, Nagashima, Hiroshi, Ohgane, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709138/
https://www.ncbi.nlm.nih.gov/pubmed/26752725
http://dx.doi.org/10.1371/journal.pone.0146498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709138/
https://www.ncbi.nlm.nih.gov/pubmed/26752725
http://dx.doi.org/10.1371/journal.pone.0146498

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