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Aberrant Wound Healing in an Epidermal Interleukin-4 Transgenic Mouse Model of Atopic Dermatitis
Wound healing in a pre-existing Th2-dominated skin milieu was assessed by using an epidermal specific interleukin-4 (IL-4) transgenic (Tg) mouse model, which develops a pruritic inflammatory skin condition resembling human atopic dermatitis. Our results demonstrated that IL-4 Tg mice had delayed wou...
Autores principales: | Zhao, Yan, Bao, Lei, Chan, Lawrence S., DiPietro, Luisa A., Chen, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709197/ https://www.ncbi.nlm.nih.gov/pubmed/26752054 http://dx.doi.org/10.1371/journal.pone.0146451 |
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