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Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability

Cadmium is a known environmental carcinogen. Exposure of Cd leads to the activation of several proto-oncogenes in cells. We investigated here the mechanism of c-Myc expression in hepatic cells under Cd treatment. The c-Myc protein and mRNA levels increased in dose- and time-dependent manners in HepG...

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Detalles Bibliográficos
Autores principales:	Tsai, Jia-Shiuan, Chao, Cheng-Han, Lin, Lih-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709241/ https://www.ncbi.nlm.nih.gov/pubmed/26751215 http://dx.doi.org/10.1371/journal.pone.0147011

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