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Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring

PURPOSE: While a variety of factors may play a role in fetal and neonatal deaths, postmaturity as a cause of stillbirth remains a topic of debate. It still is unclear, whether induction of labor at a particular gestational age may prevent fetal deaths. METHODS: A multidisciplinary working group was...

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Autores principales: Schwarz, Christiane, Schäfers, Rainhild, Loytved, Christine, Heusser, Peter, Abou-Dakn, Michael, König, Thomas, Berger, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709369/
https://www.ncbi.nlm.nih.gov/pubmed/26141654
http://dx.doi.org/10.1007/s00404-015-3795-x
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author Schwarz, Christiane
Schäfers, Rainhild
Loytved, Christine
Heusser, Peter
Abou-Dakn, Michael
König, Thomas
Berger, Bettina
author_facet Schwarz, Christiane
Schäfers, Rainhild
Loytved, Christine
Heusser, Peter
Abou-Dakn, Michael
König, Thomas
Berger, Bettina
author_sort Schwarz, Christiane
collection PubMed
description PURPOSE: While a variety of factors may play a role in fetal and neonatal deaths, postmaturity as a cause of stillbirth remains a topic of debate. It still is unclear, whether induction of labor at a particular gestational age may prevent fetal deaths. METHODS: A multidisciplinary working group was granted access to the most recent set of relevant German routine perinatal data, comprising all 5,291,011 hospital births from 2005 to 2012. We analyzed correlations in rates of induction of labor (IOL), perinatal mortality (in particular stillbirths) at different gestational ages, and fetal morbidity. Correlations were tested with Pearson’s product-moment analysis (α = 5 %). All computations were performed with SPSS version 22. RESULTS: Induction rates rose significantly from 16.5 to 21.9 % (r = 0.98; p < 0.001). There were no significant changes in stillbirth rates (0.28–0.35 per 100 births; r = 0.045; p = 0.806). Stillbirth rates 2009–2012 remained stable in all gestational age groups irrespective of induction. Fetal morbidity (one or more ICD-10 codes) rose significantly during 2005–2012. This was true for both children with (from 33 to 37 %, r = 0.784, p < 0.001) and without (from 25 to 31 %, (r = 0.920, p < 0.001) IOL. CONCLUSIONS: An increase in IOL at term is not associated with a decline in perinatal mortality. Perinatal morbidity increased with and without indiction of labor.
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spelling pubmed-47093692016-01-19 Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring Schwarz, Christiane Schäfers, Rainhild Loytved, Christine Heusser, Peter Abou-Dakn, Michael König, Thomas Berger, Bettina Arch Gynecol Obstet Maternal-Fetal Medicine PURPOSE: While a variety of factors may play a role in fetal and neonatal deaths, postmaturity as a cause of stillbirth remains a topic of debate. It still is unclear, whether induction of labor at a particular gestational age may prevent fetal deaths. METHODS: A multidisciplinary working group was granted access to the most recent set of relevant German routine perinatal data, comprising all 5,291,011 hospital births from 2005 to 2012. We analyzed correlations in rates of induction of labor (IOL), perinatal mortality (in particular stillbirths) at different gestational ages, and fetal morbidity. Correlations were tested with Pearson’s product-moment analysis (α = 5 %). All computations were performed with SPSS version 22. RESULTS: Induction rates rose significantly from 16.5 to 21.9 % (r = 0.98; p < 0.001). There were no significant changes in stillbirth rates (0.28–0.35 per 100 births; r = 0.045; p = 0.806). Stillbirth rates 2009–2012 remained stable in all gestational age groups irrespective of induction. Fetal morbidity (one or more ICD-10 codes) rose significantly during 2005–2012. This was true for both children with (from 33 to 37 %, r = 0.784, p < 0.001) and without (from 25 to 31 %, (r = 0.920, p < 0.001) IOL. CONCLUSIONS: An increase in IOL at term is not associated with a decline in perinatal mortality. Perinatal morbidity increased with and without indiction of labor. Springer Berlin Heidelberg 2015-07-04 2016 /pmc/articles/PMC4709369/ /pubmed/26141654 http://dx.doi.org/10.1007/s00404-015-3795-x Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Maternal-Fetal Medicine
Schwarz, Christiane
Schäfers, Rainhild
Loytved, Christine
Heusser, Peter
Abou-Dakn, Michael
König, Thomas
Berger, Bettina
Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring
title Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring
title_full Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring
title_fullStr Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring
title_full_unstemmed Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring
title_short Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring
title_sort temporal trends in fetal mortality at and beyond term and induction of labor in germany 2005–2012: data from german routine perinatal monitoring
topic Maternal-Fetal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709369/
https://www.ncbi.nlm.nih.gov/pubmed/26141654
http://dx.doi.org/10.1007/s00404-015-3795-x
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