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Model-Based Optimisation of Deferoxamine Chelation Therapy

PURPOSE: Here we show how a model-based approach may be used to provide further insight into the role of clinical and demographic covariates on the progression of iron overload. The therapeutic effect of deferoxamine is used to illustrate the application of disease modelling as a means to characteri...

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Detalles Bibliográficos
Autores principales: Bellanti, Francesco, Del Vecchio, Giovanni C., Putti, Maria C., Cosmi, Carlo, Fotzi, Ilaria, Bakshi, Suruchi D., Danhof, Meindert, Della Pasqua, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709373/
https://www.ncbi.nlm.nih.gov/pubmed/26555666
http://dx.doi.org/10.1007/s11095-015-1805-0

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