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Though Active on RINm5F Insulinoma Cells and Cultured Pancreatic Islets, Recombinant IL-22 Fails to Modulate Cytotoxicity and Disease in a Protocol of Streptozotocin-Induced Experimental Diabetes
Interleukin (IL)-22 is a cytokine displaying tissue protective and pro-regenerative functions in various preclinical disease models. Anti-bacterial, pro-proliferative, and anti-apoptotic properties mediated by activation of the transcription factor signal transducer and activator of transcription (S...
Autores principales: | Berner, Anika, Bachmann, Malte, Bender, Christine, Pfeilschifter, Josef, Christen, Urs, Mühl, Heiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709444/ https://www.ncbi.nlm.nih.gov/pubmed/26793108 http://dx.doi.org/10.3389/fphar.2015.00317 |
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