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Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons
Fused in Sarcoma (FUS) is a multifunctional RNA-/DNA-binding protein, which is involved in the pathogenesis of the neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). A common hallmark of these disorders is the abnormal accumulation of mutated FUS prote...
Autores principales: | Schoen, Michael, Reichel, Jochen M., Demestre, Maria, Putz, Stefan, Deshpande, Dhruva, Proepper, Christian, Liebau, Stefan, Schmeisser, Michael J., Ludolph, Albert C., Michaelis, Jens, Boeckers, Tobias M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709451/ https://www.ncbi.nlm.nih.gov/pubmed/26834559 http://dx.doi.org/10.3389/fncel.2015.00496 |
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