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Age-Dependent Degeneration of Mature Dentate Gyrus Granule Cells Following NMDA Receptor Ablation

N-methyl-D-aspartate receptors (NMDARs) in all hippocampal areas play an essential role in distinct processes of memory formation as well as in sustaining cell survival of postnatally generated neurons in the dentate gyrus (DG). In contrast to the beneficial effects, over-activation of NMDARs has be...

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Detalles Bibliográficos
Autores principales: Watanabe, Yasuhito, Müller, Michaela K., von Engelhardt, Jakob, Sprengel, Rolf, Seeburg, Peter H., Monyer, Hannah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709453/
https://www.ncbi.nlm.nih.gov/pubmed/26793056
http://dx.doi.org/10.3389/fnmol.2015.00087