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Molecular mechanism of peptide editing in the tapasin–MHC I complex

Immune recognition of infected or malignantly transformed cells relies on antigenic peptides exposed at the cell surface by major histocompatibility complex class I (MHC I) molecules. Selection and loading of peptides onto MHC I is orchestrated by the peptide-loading complex (PLC), a multiprotein as...

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Detalles Bibliográficos
Autores principales:	Fisette, Olivier, Wingbermühle, Sebastian, Tampé, Robert, Schäfer, Lars V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709564/ https://www.ncbi.nlm.nih.gov/pubmed/26754481 http://dx.doi.org/10.1038/srep19085

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