Niche Appropriation by Drosophila Intestinal Stem Cell Tumors

Mutations that inhibit differentiation in stem cell lineages are a common early step in cancer development, but precisely how a loss of differentiation initiates tumorigenesis is unclear. We investigated Drosophila intestinal stem cell (ISC) tumors generated by suppressing Notch (N) signaling, which...

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Detalles Bibliográficos
Autores principales: Patel, Parthive H., Dutta, Devanjali, Edgar, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709566/
https://www.ncbi.nlm.nih.gov/pubmed/26237646
http://dx.doi.org/10.1038/ncb3214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709566/
https://www.ncbi.nlm.nih.gov/pubmed/26237646
http://dx.doi.org/10.1038/ncb3214

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