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Downregulation of Heparanase Expression Results in Suppression of Invasion, Migration, and Adhesion Abilities of Hepatocellular Carcinoma Cells

Objective. Heparanase (HPSE) is high-expressed in most malignant tumors including hepatocellular carcinoma (HCC) and promotes cancer cell invasion and migration. The aim of the study is to explore whether HPSE enhances adhesion in metastasis of HCC cells. Methods. HPSE expressions in human HCC cells...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Peng, Luo, Jun-Sheng, Tian, Ye, Nie, Chen-Lin, Cui, Wei, Zhang, Wei-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709605/
https://www.ncbi.nlm.nih.gov/pubmed/26839882
http://dx.doi.org/10.1155/2015/241983