Development and Validation of an HPLC Method for Simultaneous Quantification of Clopidogrel Bisulfate, Its Carboxylic Acid Metabolite, and Atorvastatin in Human Plasma: Application to a Pharmacokinetic Study

A simple, sensitive, and specific reversed phase liquid chromatographic method was developed and validated for simultaneous quantification of clopidogrel, its carboxylic acid metabolite, and atorvastatin in human serum. Plasma samples were deproteinized with acetonitrile and ibuprofen was chosen as...

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Detalles Bibliográficos
Autores principales: Croitoru, Octavian, Spiridon, Adela-Maria, Belu, Ionela, Turcu-Ştiolică, Adina, Neamţu, Johny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709620/
https://www.ncbi.nlm.nih.gov/pubmed/26839733
http://dx.doi.org/10.1155/2015/892470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709620/
https://www.ncbi.nlm.nih.gov/pubmed/26839733
http://dx.doi.org/10.1155/2015/892470

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