CCL2 Serum Levels and Adiposity Are Associated with the Polymorphic Phenotypes -2518A on CCL2 and 64ILE on CCR2 in a Mexican Population with Insulin Resistance

Genetic susceptibility has been described in insulin resistance (IR). Chemokine (C-C motif) ligand-2 (CCL2) is overexpressed in white adipose tissue and is the ligand of C-C motif receptor-2 (CCR2). The CCL2 G-2518A polymorphism is known to regulate gene expression, whereas the physiological effects...

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Detalles Bibliográficos
Autores principales: Guzmán-Ornelas, Milton-Omar, Petri, Marcelo Heron, Vázquez-Del Mercado, Mónica, Chavarría-Ávila, Efraín, Corona-Meraz, Fernanda-Isadora, Ruíz-Quezada, Sandra-Luz, Madrigal-Ruíz, Perla-Monserrat, Castro-Albarrán, Jorge, Sandoval-García, Flavio, Navarro-Hernández, Rosa-Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709622/
https://www.ncbi.nlm.nih.gov/pubmed/26839895
http://dx.doi.org/10.1155/2016/5675739

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