Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity

Kisspeptins, ligands of the receptor, Gpr54, are potent stimulators of puberty and fertility. Yet, whether direct kisspeptin actions on GnRH neurons are sufficient for the whole repertoire of their reproductive effects remains debatable. To dissect out direct vs. indirect effects of kisspeptins on G...

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Detalles Bibliográficos
Autores principales: León, Silvia, Barroso, Alexia, Vázquez, María J., García-Galiano, David, Manfredi-Lozano, María, Ruiz-Pino, Francisco, Heras, Violeta, Romero-Ruiz, Antonio, Roa, Juan, Schutz, Günther, Kirilov, Milen, Gaytan, Francisco, Pinilla, Leonor, Tena-Sempere, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709743/
https://www.ncbi.nlm.nih.gov/pubmed/26755241
http://dx.doi.org/10.1038/srep19206

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