Cargando…

Endothelium-Independent Hypoxic Contraction Is Prevented Specifically by Nitroglycerin via Inhibition of Akt Kinase in Porcine Coronary Artery

Objective. Hypoxia-induced sustained contraction of porcine coronary artery is endothelium-independent and mediated by PI3K/Akt/Rho kinase. Nitroglycerin (NTG) is a vasodilator used to treat angina pectoris and acute heart failure. The present study was to determine the role of NTG in hypoxia-induce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Huixia, Li, Yanjing, An, Yuanming, He, Peixin, Wu, Liling, Gao, Yuansheng, Dou, Dou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709768/ https://www.ncbi.nlm.nih.gov/pubmed/26839558 http://dx.doi.org/10.1155/2016/2916017

Ejemplares similares

Aldehyde dehydrogenase-independent bioactivation of nitroglycerin in porcine and bovine blood vessels
por: Neubauer, Regina, et al.
Publicado: (2015)

Nitroglycerin application and coronary arteriogenesis
por: Gatzke, Nora, et al.
Publicado: (2018)

Nitroglycerine
Publicado: (1895)

Diuretics/nitroglycerin: Coronary steal syndrome: case report
Publicado: (2021)

The Dose of Nitroglycerine
Publicado: (1892)

Gentiopicroside Produces Endothelium-Independent Vasodilation by Deactivating the PI3K/Akt/Rho-Kinase Pathway in Isolated Rat Thoracic Aorta
por: Xing, Shangping, et al.
Publicado: (2021)

Early Atherosclerotic Changes in Coronary Arteries are Associated with Endothelium Shear Stress Contraction/Expansion Variability
por: Mazzi, Valentina, et al.
Publicado: (2021)

Hypothermia Inhibits Endothelium-Independent Vascular Contractility via Rho-kinase Inhibition
por: Chung, Yoon Hee, et al.
Publicado: (2018)

The Impact of Nitroglycerin on the Evaluation of Coronary Stenosis in Coronary-CT: Preliminary Study in 131 Patients
por: D’Errico, Francesca, et al.
Publicado: (2023)

Nitroglycerine in Chronic Nephritis
Publicado: (1905)

Nitroglycerine in Angina Pectoris
Publicado: (1898)

Effects of nitroglycerine on coronary flow velocity before and during adenosine provocation
por: Wittfeldt, Ann, et al.
Publicado: (2016)

Intracoronary injection of nitroglycerine can prevent unnecessary percutaneous coronary intervention
por: Nasiri-Partovi, Amirhossein, et al.
Publicado: (2022)

Endothelium-independent and calcium channel-dependent relaxation of the porcine cerebral artery by different species and strains of turmeric
por: Akter, Jesmin, et al.
Publicado: (2018)

Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway
por: Dou, Jianxin, et al.
Publicado: (2014)

Non-endothelial endothelin counteracts hypoxic vasodilation in porcine large coronary arteries
por: Hedegaard, Elise R, et al.
Publicado: (2011)

Hydroxychloroquine induces endothelium-dependent and endothelium-independent relaxation of rat aorta
por: ARSLAN, Seyfullah Oktay, et al.
Publicado: (2022)

Diagnostic Value of Nitroglycerin-Induced Headache as a Negative Predictor of Coronary Atherosclerosis
por: Cho, Sook Hee, et al.
Publicado: (2011)

Sublingual Nitroglycerin Administration in Coronary Computed Tomography Angiography: a Systematic Review
por: Takx, Richard A. P., et al.
Publicado: (2015)

Comparison of levosimendan and nitroglycerine in patients undergoing coronary artery bypass graft surgery
por: Sahu, Manoj K., et al.
Publicado: (2016)

Moderate Hypothermia Modifies Coronary Hemodynamics and Endothelium‐Dependent Vasodilation in a Porcine Model of Temperature Management
por: Bobi, Joaquim, et al.
Publicado: (2020)

Berberine Depresses Contraction of Smooth Muscle via Inhibiting Myosin Light-chain Kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Different age-independent effects of nutraceutical combinations on endothelium-mediated coronary flow reserve
por: Esposito, Roberta, et al.
Publicado: (2018)

Nitroglycerin: Hypotension: case report
Publicado: (2022)

Nebulized nitroglycerin in the emergency department
por: Ulloa, Nicolas A., et al.
Publicado: (2023)

Nitroglycerin trapping in melamine matrices
por: Schwartz, Cédric, et al.
Publicado: (2023)

Puerarin Inhibits Endothelium-Dependent Contractions in Mouse Carotid Arteries
por: Chen, Mei, et al.
Publicado: (2020)

IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways
por: Ashida, Noboru, et al.
Publicado: (2011)

Obstetric use of nitroglycerin: Anesthetic implications
por: Saroa, Richa, et al.
Publicado: (2013)

An ultra-rapid development of tachyphylaxis to nitroglycerin
por: Hegde, Harihar V, et al.
Publicado: (2014)

Abnormal cardiovascular response to nitroglycerin in migraine
por: van Oosterhout, Willebrordus PJ, et al.
Publicado: (2019)

Nitroglycerin: Lack of efficacy: case report
Publicado: (2021)

Reply to: Endothelium-dependent and -independent functions in migraineurs
por: Fujioka, Kazumi
Publicado: (2018)

Endothelium in Coronary Macrovascular and Microvascular Diseases
por: Godo, Shigeo, et al.
Publicado: (2021)

Positive effect of sublingual nitroglycerin on performance of non-contrast enhanced magnetic resonance coronary angiography
por: Heer, Tobias, et al.
Publicado: (2015)

Prehospital Administration of Aspirin and Nitroglycerin for Patients With Suspected Acute Coronary Syndrome　― A Systematic Review ―
por: Nakayama, Naoki, et al.
Publicado: (2022)

Endothelium‐derived dopamine modulates EFS‐induced contractions of human umbilical vessels
por: Britto‐Júnior, José, et al.
Publicado: (2020)

Endothelium Independent Effect of Pelargonidin on Vasoconstriction in Rat Aorta
por: Min, Young Sil, et al.
Publicado: (2018)

Nicorandil versus nitroglycerin: a pilot study
por: Singh, V, et al.
Publicado: (2011)

Nitroglycerin Tolerance in Caveolin-1 Deficient Mice
por: Mao, Mao, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_49th80cod2gbuqp4jrvs8qt9mn