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Hematopoietic Stem and Progenitor Cell Expansion in Contact with Mesenchymal Stromal Cells in a Hanging Drop Model Uncovers Disadvantages of 3D Culture

Efficient ex vivo expansion of hematopoietic stem cells with a concomitant preservation of stemness and self-renewal potential is still an unresolved ambition. Increased numbers of methods approaching this issue using three-dimensional (3D) cultures were reported. Here, we describe a simplified 3D h...

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Detalles Bibliográficos
Autores principales:	Schmal, Olga, Seifert, Jan, Schäffer, Tilman E., Walter, Christina B., Aicher, Wilhelm K., Klein, Gerd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709770/ https://www.ncbi.nlm.nih.gov/pubmed/26839560 http://dx.doi.org/10.1155/2016/4148093

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