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Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer
BACKGROUND: Grb2-associated binder 2 (Gab2), a scaffolding adaptor protein, has recently been implicated in cancer progression. However, the role of Gab2 in the progression and metastasis of colorectal cancer (CRC) remains unclear. METHODS: Gab2 expression was assessed in CRC patient specimens as we...
Autores principales: | Ding, Chenbo, Luo, Junmin, Li, Longmei, Li, Shanshan, Yang, Liwen, Pan, Hongfei, Liu, Qianyi, Qin, Huan, Chen, Chao, Feng, Jihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709914/ https://www.ncbi.nlm.nih.gov/pubmed/26754532 http://dx.doi.org/10.1186/s13046-015-0280-0 |
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