Indirect traumatic optic neuropathy

Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact remote to the optic nerve. The mechanism of injury is not understood, and there are no confirmed protocols for prevention, mitigation or treatment. Most data concerning this condition comes from case series...

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Autores principales: Singman, Eric L., Daphalapurkar, Nitin, White, Helen, Nguyen, Thao D., Panghat, Lijo, Chang, Jessica, McCulley, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709956/
https://www.ncbi.nlm.nih.gov/pubmed/26759722
http://dx.doi.org/10.1186/s40779-016-0069-2
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author Singman, Eric L.
Daphalapurkar, Nitin
White, Helen
Nguyen, Thao D.
Panghat, Lijo
Chang, Jessica
McCulley, Timothy
author_facet Singman, Eric L.
Daphalapurkar, Nitin
White, Helen
Nguyen, Thao D.
Panghat, Lijo
Chang, Jessica
McCulley, Timothy
author_sort Singman, Eric L.
collection PubMed
description Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact remote to the optic nerve. The mechanism of injury is not understood, and there are no confirmed protocols for prevention, mitigation or treatment. Most data concerning this condition comes from case series of civilian patients suffering blunt injury, such as from sports- or motor vehicle-related concussion, rather than military-related ballistic or blast damage. Research in this field will likely require the development of robust databases to identify patients with ITON and follow related outcomes, in addition to both in-vivo animal and virtual human models to study the mechanisms of damage and potential therapies.
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spelling pubmed-47099562016-01-13 Indirect traumatic optic neuropathy Singman, Eric L. Daphalapurkar, Nitin White, Helen Nguyen, Thao D. Panghat, Lijo Chang, Jessica McCulley, Timothy Mil Med Res Review Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact remote to the optic nerve. The mechanism of injury is not understood, and there are no confirmed protocols for prevention, mitigation or treatment. Most data concerning this condition comes from case series of civilian patients suffering blunt injury, such as from sports- or motor vehicle-related concussion, rather than military-related ballistic or blast damage. Research in this field will likely require the development of robust databases to identify patients with ITON and follow related outcomes, in addition to both in-vivo animal and virtual human models to study the mechanisms of damage and potential therapies. BioMed Central 2016-01-11 /pmc/articles/PMC4709956/ /pubmed/26759722 http://dx.doi.org/10.1186/s40779-016-0069-2 Text en © Singman et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Singman, Eric L.
Daphalapurkar, Nitin
White, Helen
Nguyen, Thao D.
Panghat, Lijo
Chang, Jessica
McCulley, Timothy
Indirect traumatic optic neuropathy
title Indirect traumatic optic neuropathy
title_full Indirect traumatic optic neuropathy
title_fullStr Indirect traumatic optic neuropathy
title_full_unstemmed Indirect traumatic optic neuropathy
title_short Indirect traumatic optic neuropathy
title_sort indirect traumatic optic neuropathy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709956/
https://www.ncbi.nlm.nih.gov/pubmed/26759722
http://dx.doi.org/10.1186/s40779-016-0069-2
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