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Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus

BACKGROUND: Current evidence indicates that estrogens, in particular 17β-estradiol (E2), play a crucial role in the gender bias of autoimmune diseases although the underlying molecular mechanisms have not yet been fully elucidated. Immune cells have estrogen receptors (ERs), i.e., ERα and ERβ, that...

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Detalles Bibliográficos
Autores principales:	Maselli, Angela, Conti, Fabrizio, Alessandri, Cristiano, Colasanti, Tania, Barbati, Cristiana, Vomero, Marta, Ciarlo, Laura, Patrizio, Mario, Spinelli, Francesca Romana, Ortona, Elena, Valesini, Guido, Pierdominici, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709986/ https://www.ncbi.nlm.nih.gov/pubmed/26759713 http://dx.doi.org/10.1186/s13293-016-0057-y

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